Circulatory T-cadherin is a potential biomarker for atherosclerosis
نویسندگان
چکیده
T-cadherin, a special member of cadherin family, expresses with blood circulation involving the heart i.e. CVS. Cadherin is connected healthy conditions an individual and normal functioning cardio-vascular metabolism. T-cadherin mainly associated vascular system human. Previous studies analysed this been unexpressed within fat storing tissues adipose tissue peri-aortic peri-coronary, it present endothelium as well in vascularized smooth muscular cells which includes area nearby coronary vessels aorta. The site attention-grabbing because particularly related to atherosclerosis cardiovascular disease (CVD). - protein acting receptor for low density lipoproteins (LDL). It may act biomarker atherosclerosis. on showed that has cardio-protective role. Furthermore, research essential enumerate function T-cadherin. can be important therapeutic target developing new medicine decrease incident its complications.
منابع مشابه
E-cadherin: A potential biomarker of colorectal cancer prognosis
Colorectal cancer (CRC) is a common and lethal disease. It is the third most common type of cancer in the world, behind lung and breast cancer, with almost 1.4 million new cases diagnosed in 2012. The risk of developing CRC is influenced by environmental and genetic factors. Adenocarcinomas comprise the vast majority (98%) of CRCs. A patient's likelihood of survival is associated with the tumor...
متن کاملLOX-1 protein, A Biomarker in the Prognosis of Atherosclerosis
LOX-1 is a class E scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved in endothelial dysfunctions, monocyte adhesion, the proliferation, migration, and apoptosis of smooth muscle cells, foam cell formation, platelet activation, as well as plaque instability; all of these events are critical in the pathogenesis of atherosclerosis. These LOX-1-dependent bio...
متن کاملT-cadherin is present on endothelial microparticles and is elevated in plasma in early atherosclerosis.
AIMS The presence of endothelial cell (EC)-derived surface molecules in the circulation is among hallmarks of endothelial activation and damage in vivo. Previous investigations suggest that upregulation of T-cadherin (T-cad) on the surface of ECs may be a characteristic marker of EC activation and stress. We investigated whether T-cad might also be shed from ECs and in amounts reflecting the ex...
متن کاملHigh-sensitivity cardiac troponin T is a biomarker for atherosclerosis in systemic lupus erythematous patients: a cross-sectional controlled study
BACKGROUND Cardiovascular disease (CVD) is the main cause of death in systemic lupus erythematous (SLE) patients. The Framingham score underestimates the risk for CVD in this population. Our study aimed to determine whether serum high-sensitivity cardiac troponin T (HS-cTnT) might help to identify SLE patients at risk for CVD. METHODS The presence of carotid plaques was prospectively assessed...
متن کاملSerum Uric Acid as a Potential Concomitant with Carotid Atherosclerosis
Background: Common carotid intima-media thickness (CC-IMT) measured by ultrasonography as a non-invasive method is nowadays known as a marker for early atherosclerosis. Objectives: Survey the relationship between serum uric acid and carotid intima-media thickness considering hypertension. Materials and Methods: This study was designed as a comparative cross-sectional study in northern Ira...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedicine
سال: 2022
ISSN: ['2211-8020', '2211-8039']
DOI: https://doi.org/10.51248/.v42i3.1591